Ohio State Hosts Oregon in Week 10 With Backup Quarterbacks

The No. 12 Ohio State Buckeyes will play the No. 23 Oregon Ducks on Saturday, November 7, 2026. The game is scheduled for 3:30 p.m. ET at Ohio Stadium in Columbus. CBS and Paramount+ will carry the broadcast. Both teams are missing their starting quarterbacks for this contest.

Ohio State holds a 6-2 record, with a 4-1 mark in conference play. The Buckeyes lost their previous game to unranked USC on Saturday, ending a five-game winning streak. The Trojans won that matchup 30-18. Oregon sits at 5-3 overall and 3-2 in the Big Ten. The Ducks won their last game 34-26 against then-No. 20 Northwestern in Week 9.

Julian Sayin will not play for Ohio State due to an arm injury. Dante Moore is sidelined for Oregon with a concussion. Luke Fahey, a true freshman, stepped in for Ohio State. He passed for 260 yards and one touchdown without turnovers in the USC game. Dylan Raiola is Oregon's substitute. He threw for 336 yards and three touchdowns in his last appearance.

The all-time series between these teams stands at 3-2 in favor of Ohio State. The last four meetings have produced more than 60 combined points. All four of Ohio State's home games in 2026 have gone over the point limit. Two of Oregon's three road games this season have also exceeded the total.

Betting markets list Ohio State as 7.5-point favorites. The over/under is set at 45.5 points. SportsLine predicts the over will hit in 56% of 10,000 simulations. The model notes the over has a 5-1 record in Oregon's last six games as an underdog. One side of the spread is expected to cover in more than 60% of simulated scenarios.

The SportsLine model entered Week 10 with an 80-77 record on top-rated college football picks. Both offenses are expected to score heavily despite the quarterback changes. The outcome will depend on how each team manages the transition and maintains scoring efficiency.

The game serves as a test for both programs in the latter part of the regular season. Projections suggest the two backups could combine for over 500 passing yards. The high projected point total reflects confidence in both offensive units.